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DeepSomatic 1.10.0

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@kishwarshafin kishwarshafin released this 05 Mar 23:37

DeepSomatic:

  • Steamlining input parameters: run_deepsomatic now reads parameters from model.example_info.json files which must be present with the models to run.
  • Small model in DeepSomatic: Introduced small models for tumor-normal modes in DeepSomatic improving the runtime between 12% to 40%.

Contributions:

  • Ehud Amitai (@ehudamitai) from Ultima genomics for the algorithm development of multiallelic variant post-processing method that is available as “product” option.
  • Vasiliy Strelnikov (@vaxyzek) for streamlining the run_deepvariant script by enabling automatic flag loading using model.example_info.json files.
  • Sowmiya Nagarajan (@sonagarajan) - for helping to update the RNA-seq model.
  • Shezan Rohinton Mirzan (@shezanmirzan) for migrating small model to Keras 3 and modernizing core infrastructure.
  • Francisco Unda (@fcoUnda) for enhancing read sampling stability, fixing non-determinism, and creating robust read sampling approach at high coverages.
  • Alec Zhang (@az-e) for providing essential internal updates and maintenance to the codebase.